Genetics of the human face: Identification of large-effect single gene variants. DJM Crouch, B Winney, WP Koppen, WJ Christmas, K Hutnik, T Day, D Meena, A Boumertit, P Hysi, A Nessa, TD Spector, J Kittler, WF Bodmer.

Date: October 2017 Source: PNAS | Proceedings of the National Academy of Sciences of the United States of America, doi: 10.1073/pnas.1708207114. Significance: The human face is extraordinarily variable, and the extreme similarity of the faces of identical twins indicates that most of this variability is genetically determined. We have devised an approach to increase the […]

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Heritability maps of human face morphology through large-scale automated three-dimensional phenotyping. D Tsagkrasoulis, P Hysi, T Spector, G Montana.

Date: August 2016 Source: ResearchGate Abstract: The human face is a complex trait under strong genetic control, as evidenced by the striking visual similarity between twins. Nevertheless, heritability estimates of facial traits have often been surprisingly low or difficult to replicate. Furthermore, the construction of facial phenotypes that correspond to naturally perceived facial features remains […]

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