Validation of a new three-dimensional imaging system using comparative craniofacial anthropometry. FB Naini, S Akram, J Kepinska, U Garagiola, F McDonald, D Wertheim.

Date: August 2017. Source: Maxillofacial Plastic and Reconstructive Surgery (2017) 39: 23. Background: The aim of this study is to validate a new three-dimensional craniofacial stereophotogrammetry imaging system (3dMDface) through comparison with manual facial surface anthropometry. The null hypothesis was that there is no difference between craniofacial measurements using anthropometry vs. the 3dMDface system. Methods: […]

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Trisomy 21 and Facial Developmental Instability. JM Starbuck, TM Cole III, RH Reeves, and JT Richtsmeier.

Date: February 2013. Source: American Journal of Physical Anthropology, Volume 151, Issue 1, pp 49-57. Abstract: The most common live-born human aneuploidy is trisomy 21, which causes Down syndrome (DS). Dosage imbalance of genes on chromosome 21 (Hsa21) affects complex gene-regulatory interactions and alters development to produce a wide range of phenotypes, including characteristic facial dysmorphology. Little is known about how […]

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Image Fusion in Preoperative Planning

This article presents a comprehensive overview of generating a digital Patient-Specific Anatomic Reconstruction (PSAR) model of the craniofacial complex as the foundation for a more objective surgical planning platform. The technique explores fusing the patient’s 3D radiograph with the corresponding high-precision 3D surface image within a biomechanical context. As taking 3D radiographs has been common […]

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Morphological Integration of Soft-Tissue Facial Morphology in Down Syndrome and Siblings. J Starbuck, RH Reeves, and J Richtsmeier.

Date: June 2011. Source: American Journal of Physical Anthropology, 146(4): 560–568. Abstract: Down syndrome (DS), resulting from trisomy of chromosome 21, is the most common live-born human aneuploidy. The phenotypic expression of trisomy 21 produces variable, though characteristic, facial morphology. Although certain facial features have been documented quantitatively and qualitatively as characteristic of DS (e.g., […]

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On the Antiquity of Trisomy 21: Moving Towards a Quantitative Diagnosis of Down Syndrome in Historic Material Culture. John M. Starbuck

Date: 2011 Source: Journal of Contemporary Anthropology, Vol. II (2011), Iss. 1. Abstract: Down syndrome was first medically described as a separate condition from other forms of cognitive impairment in 1866. Because it took so long for Down syndrome to be recognized as a clinical entity deserving its own status, several investigators have questioned whether […]

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