A preliminary investigation of the effects of prenatal alcohol exposure on facial morphology in children with Autism Spectrum Disorder. DW Tan, YZ Foo, J Downs, A Finlay-Jones, H Leonard, M Licari, N Mullan, M Symons, KJ Varcin, AJO Whitehouse, GA Alvares.

Date: August 2020. Source:  Alcohol. Volume 86, Pages 75-80. Abstract: Alcohol exposure during pregnancy has been associated with altered brain development and facial dysmorphology. While autism spectrum disorder (ASD) is not specifically related to distinct facial phenotypes, recent studies have suggested certain facial characteristics—increased facial masculinity and asymmetry—may be associated with ASD and its clinical…

Sex‐specific variation in facial masculinity/ femininity associated with autistic traits in the general population. DW Tan, MT Maybery, L Ewing, JX Tay, PR Eastwood, AJO Whitehouse.

Date: December 2019. Source: British Journal Psychology. doi: 10.1111/bjop.12436. (Online) Abstract: Reports linking prenatal testosterone exposure to autistic traits and to a masculinized face structure have motivated research investigating whether autism is associated with facial masculinization. This association has been reported with greater consistency for females than for males, in studies comparing groups with high…

Hypermasculinised facial morphology in boys and girls with Autism Spectrum Disorder and its association with symptomatology. DW Tan, SZ Gilani, MT Maybery, A Mian, A Hunt, M Walters, AJO Whitehouse.

Date: August 2017 Source: nature.com SCiENtifiC REporTS | 7: 9348 Abstract: Elevated prenatal testosterone exposure has been associated with Autism Spectrum Disorder (ASD) and facial masculinity. By employing three-dimensional (3D) photogrammetry, the current study investigated whether prepubescent boys and girls with ASD present increased facial masculinity compared to typically-developing controls. There were two phases to…

Autism: Comparative Genomics and Interactomics. C Barth, N Bishop.

Date: January 2014 Source: Comprehensive Guide to Autism, pp 2853–2880. New York: Springer, 2014. Abstract: Many common human neurological disorders, including autism spectrum disorder (ASD), epilepsy, Alzheimer’s disease, attention-deficit/hyperactivity disorder (ADHD), and schizophrenia, have complex genetics and inheritance patterns. While understanding the molecular mechanisms of single-gene disorders is comparatively straightforward, complex diseases are, by their…