B_AJMG

A predictive model for obstructive sleep apnea and Down syndrome. BG Skotko et al.

Date: January 2017 Source: American Journal of Medical Genetics. Abstract: Obstructive sleep apnea (OSA) occurs frequently in people with Down syndrome (DS) with reported prevalences ranging between 55% and 97%, compared to 1–4% in the neurotypical pediatric population. Sleep studies are often uncomfortable, costly, and poorly tolerated by individuals with DS. The objective of this […]

Read More
B_PLOS1

Genetic and Environmental Contributions to Facial Morphological Variation: A 3D Population-Based Twin Study. J Djordjevic, AI Zhurov, S Richmond, Visigen Consortium.

Date: September 2016 Source: PLoS One. 11(9):e0162250. Introduction: Facial phenotype is influenced by genes and environment; however, little is known about their relative contributions to normal facial morphology. The aim of this study was to assess the relative genetic and environmental contributions to facial morphological variation using a three-dimensional (3D) population-based approach and the classical […]

Read More
B_PLOS1

Genome-Wide Association Study Reveals Multiple Loci Influencing Normal Human Facial Morphology. JR Shaffer, E Orlova, MK Lee, EJ Leslie, ZD Raffensperger, CL Heike, more…

Date: August 2016 Source: PLOS Genetics Abstract: Numerous lines of evidence point to a genetic basis for facial morphology in humans, yet little is known about how specific genetic variants relate to the phenotypic expression of many common facial features. We conducted genome-wide association meta-analyses of 20 quantitative facial measurements derived from the 3D surface […]

Read More
b_heritability-maps

Heritability maps of human face morphology through large-scale automated three-dimensional phenotyping. D Tsagkrasoulis, P Hysi, T Spector, G Montana.

Date: August 2016 Source: ResearchGate Abstract: The human face is a complex trait under strong genetic control, as evidenced by the striking visual similarity between twins. Nevertheless, heritability estimates of facial traits have often been surprisingly low or difficult to replicate. Furthermore, the construction of facial phenotypes that correspond to naturally perceived facial features remains […]

Read More
B_ABCNEWS australia

New expert panel hoping to unlock mysteries of undiagnosed diseases.

Date: 23 Jul 2016, 10:23p Source: ABC News Australia Author: Claire Moodie Jessica’s mystery disease tackled by expert panel The family of a Perth girl is cautiously hoping a panel of experts will be able to diagnose the mystery condition which has baffled the 11-year-old’s doctors for years. 190,000 West Australians affected by rare diseases. […]

Read More
b_umcg_vandermeer

3D Workflows in Orthodontics, Maxillofacial Surgery and Prosthodontics. Wicher J. van der Meer.

Date: 2016 Source: PhD Thesis Abstract: 3D workflows should result in clinical procedures that help clinicians to get better results with less effort and at lower costs. In other words, the 3D technology should make complex and difficult clinical procedures simpler and easier with reduced costs for healthcare. If 3D workflows are available with a […]

Read More
B_Cleft Palate Journal

Hypertelorism and Orofacial Clefting Revisited: An Anthropometric Investigation. SM Weinberg, EJ Leslie, JT Hecht, GL Wehby, FWB Deleyiannis, LM Moreno, K Christensen, ML Marazita.

Date: June 2016. ONLINE AHEAD OF PRINT Source: The Cleft Palate-Craniofacial Journal. Objective: Since the 1960s, multiple studies have reported a tendency toward hypertelorism in individuals with nonsyndromic orofacial clefts (OFCs). However, the association between specific cleft types and increased interorbital distance has been inconsistent. Using three-dimensional (3D) surface imaging, we tested whether different forms […]

Read More
b_current-biology

The MC1R Gene and Youthful Looks. F Liu, MA Hamer, J Deelen, JS Lall, L Jacobs, D van Heemst, PG Murray, A Wollstein, AJM de Craen, HW Uh, CQ Zeng, A Hofman, AG Uitterlinden, JJ Houwing-Duistermaat, LM Pardo, M Beekman, PE Slagboom, T Nijsten, M Kayser, DA Gunn.

Date: April 2016. Source: Current Biology, Volume 26, Issue 9, 9 May 2016, Pages 1213–1220. Highlights: • We present the first genetic associations with how old people look (perceived age) • Variants in MC1R, a pigmentation gene, significantly associated with perceived age • The MC1R association was independent of wrinkling, skin color, and sun exposure […]

Read More
b_iNTL dERMATOLOGY

Infantile hemangioma status by dynamic infrared thermography: A preliminary study. SA Burkes, M Patel, DM Adams, AM Hammill, KP Eaton, RR Wickett, MO Visscher.

Date: April 2016. Source: International Journal of Dermatology. Background: Infantile hemangiomas (IH) are initially warm due to increased proliferation and perfusion then involute with apoptosis and reduced perfusion. Objective quantitative evaluation of IH treatment response is essential for improving outcomes. We applied a functional imaging method, dynamic infrared (IR) thermography, to investigate IH status versus […]

Read More
b_biology-of-sex-differences

Using the 3D Facial Norms Database to investigate craniofacial sexual dimorphism in healthy children, adolescents, and adults. MJ Kesterke, ZD Raffensperger, CL Heike, ML Cunningham, JT Hecht, CH Kau, NL Nidey, LM Moreno, GL Wehby, ML Marazita, and SM Weinberg.

Date: April 2016 Source: Biology of Sex Differences. Background: Although craniofacial sex differences have been extensively studied in humans, relatively little is known about when various dimorphic features manifest during postnatal life. Using cross-sectional data derived from the 3D Facial Norms data repository, we tested for sexual dimorphism of craniofacial soft-tissue morphology at different ages. […]

Read More
B_Cleft Palate Journal

Measuring Symmetry in Children With Unrepaired Cleft Lip: Defining a Standard for the Three-Dimensional Mid-facial Reference Plane. J Wu, C Heike, C Birgfeld, K Evans, M Maga, C Morrison, B Saltzman, L Shapiro, R Tse.

Date: March 2016 (Online ahead of print) Source: The Cleft Palate-Craniofacial Journal. Objective: Quantitative measures of facial form to evaluate treatment outcomes for cleft lip (CL) are currently limited. Computer-based analysis of three-dimensional (3D) images provides an opportunity for efficient and objective analysis. The purpose of this study was to define a computer-based standard of […]

Read More
B_Clinical Genetics

Molecular genetic analysis in 14 czech kabuki syndrome patients is confirming the utility of phenotypic scoring. J Paděrová; A Holubová; M Simandlová; A Puchmajerová; M Vlčková; M Malíková; R Pourová; S Vejvalková; M Havlovicová; M Šenkeříková; N Ptáková; J Drábová; J Geryk; A Maver; A Křepelová; M Macek.

Date: February 2016. Source: Clinical Genetics. The International Journal of Genetics, Molecular, and Personalized Medicine. Abstract: Kabuki syndrome (KS) is a dominantly inherited disorder mainly due to de novo pathogenic variation in KMT2D or KDM6A genes. Initially, a representative cohort of 14 Czech cases with clinical features suggestive of KS was analyzed by experienced clinical […]

Read More
B_ajo-do

Facial morphology in children and adolescents with juvenile idiopathic arthritis and moderate to severe temporomandibular joint involvement. YJ Hsieh, TA Darvann, NV Hermann, P Larsen, YF Liao, J Bjoern-Joergensen, S Kreiborg.

Date: February 2016 Source: American Journal of Orthodontics & Dentofacial Orthopedics. Volume 149, Issue 2, Pages 182–191. Highlights: • We evaluated lateral facial morphology of juvenile idiopathic arthritis patients with moderate and severe TMJ involvement. • Differences in their lateral facial morphologies between unilateral and bilateral TMJ involvement were also assessed. Introduction: The aims of […]

Read More
B_IEEE

Analysis of facial muscle activation in children with autism using 3D imaging. MD Samad, JL Bobzien, JW Harrington, KM Iftekharuddin.

Date: November 2015. Source: 2015 IEEE International Conference on Bioinformatics and Biomedicine (BIBM), Pages 337-342. Washington, DC. Abstract: Autism Spectrum Disorder (ASD) impairs an individual’s non-verbal skills including natural and contextual facial expressions. Such impairments may manifest as odd facial expressions (facial oddity) based on subjective evaluations of facial images. A few studies conducted on […]

Read More
B_Cleft Palate Journal

The 3D Facial Norms Database: Part 1. A Web-Based Craniofacial Anthropometric and Image Repository for the Clinical and Research Community.

Date: October 2015 [Epub ahead of print]. Source: Cleft Palate Craniofacial Journal. Background: Although craniofacial sex differences have been extensively studied in humans, relatively little is known about when various dimorphic features manifest during postnatal life. Using cross-sectional data derived from the 3D Facial Norms data repository, we tested for sexual dimorphism of craniofacial soft-tissue […]

Read More
B_IOC

Analysis of Characteristic Facial Features in Patients with Hypodontia using Three-Dimensional Imaging. S Ani, J Collins, S Cunningham, C Ruff.

Date: September 2015. Source: 8th International Orthodontic Congress 2015, London. Study Aims: To analyse the facial features associated with hypodontia using 3D surface imaging and establish the effect of its severity on facial morphology. Method: A study group of 70 hypodontia patients and a control group of 40 Class I patients were recruited to allow […]

Read More
B_HMPFuMD

Craniofacial Image Analysis. E Mercan, I Atmosukarto, J Wu, S Liang, LG Shapiro.

Date: July 2015. Source: Health Monitoring and Personalized Feedback using Multimedia Data. Springer. Abstract: Craniofacial researchers have used anthropometric measurements taken directly on the human face for research and medical practice for decades. With the advancements in 3D imaging technologies, computational methods have been developed for the diagnoses of craniofacial syndromes and the analysis of […]

Read More
B_MedicineScience

Comparison of the Facial Morphologies of Identical Twins Using Three-Dimensional Photography: A Case Report. Sedat Altindis, Erdem Hatunoglu, Emine Toptan.

Date: July 2015 Source: Medicine Science | International Medical Journal. Abstract: The facial morphologies of identical twins were compared using the 3dMD three-dimensional (3D) photogrammetry system. 3D images of the faces of 27-year-old identical twins were acquired and then superimposed. The differences were shown in a color histogram generated using 3dMD Vultus software. The faces […]

Read More
B_Plastic & Reconstructive J

Unilateral Cleft Lip Repair Using the Anatomical Subunit Approximation: Modifications and Analysis of Early Results in 100 Consecutive Cases. R Tse, S Lien.

Date: July 2015. Source: Plastic and Reconstructive Surgery, 136(1):119-30. Abstract: The “Anatomic Subunit Approximation” for unilateral cleft lip repair has gained acceptance, however, outcomes have not been reported since the original description. The purpose of this study is to report the experience using this technique. Methods: One hundred two consecutive patients underwent primary cleft lip […]

Read More
B_ECC 2015

Methods for Extraction and Analysis of Shape and Asymmetry from Craniofacial 3D Images. TA Darvann.

Date: June 24, 2015. Source: European Craniofacial Congress 2015, Gothenburg, Sweden. Summary: Being able to compare images is one of the core technologies of medical image analysis. In order to quantify change, e.g. due to growth or surgery, it is necessary to compare two or more images. And as part of population studies it is […]

Read More
B_Seminars in Orthodontics

3D digital surface imaging for quantification of facial development and asymmetry in juvenile idiopathic arthritis. NV Hermann, TA Darvann, P Larsen, S Kreiborg.

Date: June 2015. Source: Seminars in Orthodontics, Volume 21, Issue 2, Pages 121–124. Abstract: 3D digital surface imaging (digital stereophotogrammetry or “3D photography”) is becoming an increasingly popular tool for quantification of the face, in clinical contexts as well as for research. The modality is easy to apply and is free from motion artifacts and […]

Read More
B_IEEE

A Solution to Face-to-Face Contact in Tele-Presence Systems. X Zhou, P Boulanger.

Date: June 2015 Source: 2015 12th Conference on Computer and Robot Vision (CRV) Proceedings (p 230 – 236), Halifax, Canada. Abstract: In tele-presence systems, direct face-to-face contact, is essential for emotional communication as it carries non-verbal clues. In commercial products, face-to-face contact is approximated by using either a large semi-transparent mirror to project an image […]

Read More
B_Cell ResearchJ

Three-dimensional human facial morphologies as robust aging markers. W Chen, W Qian, G Wu, W Chen, B Xian, X Chen, Y Cao, CD Green, F Zhao, K Tang, JD Han.

Date: May 2015. Source: Journal of Cell Research, 25, 574-587. Abstract: Aging is associated with many complex diseases. Reliable prediction of the aging process is important for assessing the risks of aging-associated diseases. However, despite intense research, so far there is no reliable aging marker. Here we addressed this problem by examining whether human 3D […]

Read More
B_Twin Research J

Comparing Facial 3D Analysis With DNA Testing to Determine Zygosities of Twins. V Vuollo, M Sidlauskas, A Sidlauskas, V Harila, L Salomskiene, A Zhurov, L Holmström, P Pirttiniemi, T Heikkinen.

Date: June 2015. Source: Twin Research and Human Genetics, Volume 18, Issue 03, pp 306-313. Abstract: The aim of this study was to compare facial 3D analysis to DNA testing in twin zygosity determinations. Facial 3D images of 106 pairs of young adult Lithuanian twins were taken with a stereophotogrammetric device (3dMD, Atlanta, Georgia) and […]

Read More
B_IADR

Validation of a new method to measure facial soft tissue movements. CA Trotman, T Lu, V Sirianna.

Date: May 2015. Source: International Association for Dental Research, Boston, USA. Poster: #4342. Authors: CA Trotman, T Lu, V Sirianna. School of Dentistry, University of North Carolina at Chapel Hill, USA.

Read More
B_JIMD Reports

Monitoring of Therapy for Mucopolysaccharidosis Type I Using Dysmorphometric Facial Phenotypic Signatures. Stefanie Kung, M Walters, P Claes, P LeSouef, J Goldblatt, A Martin, S Balasubramaniam, G Baynam.

Date: March 2015. Source: JIMD Reports 2015, Springer. Abstract: There is a pattern of progressive facial dysmorphology in mucopolysaccharidosis type I (MPS I). Advances in 3D facial imaging have facilitated the development of tools, including dysmorphometrics, to objectively and precisely detect these facial phenotypes. Therefore, we investigated the application of dysmorphometrics as a noninvasive therapy-monitoring […]

Read More
B_Ortho_Craniofacial Research J

Prenatal sex hormones, digit ratio, and face shape in adult males. SM Weinberg, TE Parsons, ZD Raffensperger.

Date: February 2015. Source: Orthodontics & Craniofacial Research, 18(1):21-6. Objectives: Several reports have demonstrated a relationship between second to fourth digit ratio (2D:4D) and facial shape, suggesting that prenatal sex hormones play a role in the development of the craniofacial complex. Using 3D surface imaging and geometric morphometrics, we test the hypothesis that decreased digit […]

Read More
B_Euro J Orthodontics

Regional facial asymmetries in unilateral orofacial clefts. MA Kuijpers, DJ Desmedt, RM Nada, SJ Bergé, PS Fudalej, TJJ Maal.

Date: February 2015. Source: The European Journal of Orthodontics. Objectives: Assess facial asymmetry in subjects with unilateral cleft lip (UCL), unilateral cleft lip and alveolus (UCLA), and unilateral cleft lip, alveolus, and palate (UCLP), and to evaluate which area of the face is most asymmetrical. Methods: Standardized three-dimensional facial images of 58 patients (9 UCL, […]

Read More
B_Cleft Palate Journal

Monobloc Le Fort III Distraction Osteogenesis for Correction of Severe Fronto-orbital and Midface Hypoplasia in Pediatric Crouzon Syndrome. F Hariri, LK Cheung, ZA Rahman, V Mathaneswaran, D Ganesan.

Date: February 2015. Source: The Cleft Palate-Craniofacial Journal. Abstract: In severe syndromic craniosynostosis, distraction osteogenesis (DO) provides superior segmental advancement and allows progressive clinical monitoring to ensure that adequate skeletal expansion is achieved. We report two cases of Crouzon syndrome involving a 3-year-old boy and a 4-year-old girl, who were both treated with monobloc Le […]

Read More
B_Daily Mail

Does your FACE give away signs of autism? Researchers develop new 3D scanning software to check for signs in children. Daily Mail.

Date: January 16, 2015. Source: Daily Mail.com. Author: Mark Prigg. Highlights: Researchers developed special software to look for signs of the disorder Say their work could lead to a low cost screening tool for young children Could also help pinpoint genetic causes of the disorder

Read More
B_Cleft Palate Journal

Quantitative Assessment of Facial Asymmetry Using Three-Dimensional Surface Imaging in Adults: Validating the Precision and Repeatability of a Global Approach. D Kornreich, AA Mitchell, BD Webb, I Cristian, EW Jabs.

Date: December 2014. Source: The Cleft Palate-Craniofacial Journal. Objective: Comparison of global versus landmark analyses of facial asymmetry using three-dimensional photogrammetry to establish a precise method for evaluating facial asymmetry. Design: The landmark-based approach utilized anthropometric data points. Our global approach involved registration of mirror images, independent of a midplane, to calculate a root mean […]

Read More
B_Lugano

The Latest Applications of Temporal-3D (4D) to Support Clinical Initiatives. CR Lane.

Date: October 2014. Source: 3D Body Scanning Conference 2014, Lugano, Switzerland. Abstract: In 2011 3dMD and the University of North Carolina at Chapel Hill, School of Dentistry, were awarded a ground-breaking US NIH Grant (STTR Grant No. 2R42DE019742-02) to study the facial dynamics of children who had received corrective treatment for facial conditions. The recruitment […]

Read More
B_Lugano

Establishment of Reference Frame for Sequential Facial Biometrics. L Zou, P Hao, M McCarthy

Date: October 2014. Source: 3D Body Scanning Conference 2014, Lugano, Switzerland. Abstract: Facial biometrics as an objective, accurate, living parts measurement methodology, is widely used in assisting diagnose and treatment plan within the practice of medicine and dentistry. It is particularly popular that the quantification of changes before and after a clinical intervention. However the […]

Read More
B_AI in Medicine

Biomedical visual data analysis to build an intelligent diagnostic decision support system in medical genetics. K Kuru, M Niranjan, Y Tunca, E Osvank, T Azim.

Date: October 2014. Source: Artificial Intelligence in Medicine, 62(2):105-18. Background: In general, medical geneticists aim to pre-diagnose underlying syndromes based on facial features before performing cytological or molecular analyses where a genotype–phenotype interrelation is possible. However, determining correct genotype–phenotype interrelationships among many syndromes is tedious and labor-intensive, especially for extremely rare syndromes. Thus, a computer-aided […]

Read More
B_IEEE

Learning to Rank the Severity of Unrepaired Cleft Lip Nasal Deformity on 3D Mesh Data. J Wu, R Tse, LG Shapiro.

Date: August 2014. Source: Int. Conference on Pattern Recognition (ICPR) 2014, Stockholm, Sweden. © IEEE. Pages 460-464. Abstract: Cleft lip is a birth defect that results in deformity of the upper lip and nose. Its severity is widely variable and the results of treatment are influenced by the initial deformity. Objective assessment of severity would […]

Read More
B_Int_J_Morphology

Quantitative Evaluation of the Facial Morphology of a Tolteca Figurine from Mexico using Geometric Morphometric Approaches. JM Starbuck.

Date: June 2014. Source: International Journal of Morphology. Volume 32, Number 2, pp 499–509. Summary: Morphometric approaches can be combined with 2D or 3D imaging to quantitatively evaluate craniofacial medical conditions depicted in material culture and to learn more about the culture being studied. A terra-cotta figurine (circa 500 A.D.) from the Tolteca culture of […]

Read More
B_j anatomy

Exploratory genotype–phenotype correlations of facial form and asymmetry in unaffected relatives of children with non-syndromic cleft lip and/or palate. SF Miller, SM Weinberg, NL Nidey, DK Defay, ML Marazita, GL Wehby, LM Moreno Uribe.

Date: June 2014 Source: Journal of Anatomy, Volume 224, Issue 6, pp 688-709. Abstract: Family relatives of children with nonsyndromic cleft lip with or without cleft palate (NSCL/P) who presumably carry a genetic risk yet do not manifest overt oral clefts, often present with distinct facial morphology of unknown genetic etiology. This study investigates distinct […]

Read More
B_Plastic & Reconstructive J

Reliability of Nasolabial Anthropometric Measures Using Three-Dimensional Stereophotogrammetry in Infants with Unrepaired Unilateral Cleft Lip. R Tse, L Booth, K Keys, B Saltzman, E Stuhaug, H Kapadia, C Heike.

Date: April 2014 Source: Plastic & Reconstructive Surgery, Journal of the American Society of Plastic Surgery, Volume 133, Issue 4, p 530e–542e. Background: Surgical and orthodontic treatment of unilateral cleft lip +/– palate can produce dramatic changes in nasolabial form; however, the lack of ideal methods with which to objectively document three-dimensional form limits the […]

Read More
B_Claes_Mar 2014

Modeling 3D Facial Shape from DNA. P Claes, DK Liberton, K Daniels, KM Rosana, EE Quillen, LN Pearson, B McEvoy, M Bauchet, AA Zaidi, W Yao, H Tang, GS Barsh, DM Absher, MD Shriver.

Date: March 2014 Source: PLOS Genetics. Abstract: Human facial diversity is substantial, complex, and largely scientifically unexplained. We used spatially dense quasi-landmarks to measure face shape in population samples with mixed West African and European ancestry from three locations (United States, Brazil, and Cape Verde). Using bootstrapped response-based imputation modeling (BRIM), we uncover the relationships […]

Read More
B_Wnd Rep&Regen

Digital imaging analysis to assess scar phenotype. BJ Smith, N Nidey, SF Miller, LMM Uribe, CL Baum, GS Hamilton, GL Wehby, M Dunnwald.

Date: March-April 2014. Source: Wound Repair and Regeneration, Volume 22, Issue 2, pages 228–238. Abstract: In order to understand the link between the genetic background of patients and wound clinical outcomes, it is critical to have a reliable method to assess the phenotypic characteristics of healed wounds. In this study, we present a novel imaging […]

Read More
B_Comp G2Autism

Autism: Comparative Genomics and Interactomics. C Barth, N Bishop.

Date: January 2014 Source: Comprehensive Guide to Autism, pp 2853–2880. New York: Springer, 2014. Abstract: Many common human neurological disorders, including autism spectrum disorder (ASD), epilepsy, Alzheimer’s disease, attention-deficit/hyperactivity disorder (ADHD), and schizophrenia, have complex genetics and inheritance patterns. While understanding the molecular mechanisms of single-gene disorders is comparatively straightforward, complex diseases are, by their […]

Read More
B_PLOS1

Detecting Genetic Association of Common Human Facial Morphological Variation Using High Density 3D Image Registration. S Peng, J Tan, S Hu, H Zhou, J Guo, L Jin, K Tang.

Date: December 2013. Source: PLoS Computational Biology, Public Library of Science. Abstract: Human facial morphology is a combination of many complex traits. Little is known about the genetic basis of common facial morphological variation. Existing association studies have largely used simple landmark-distances as surrogates for the complex morphological phenotypes of the face. However, this can […]

Read More
B_UI_Rogers

Indiana University visualization experts help doctors diagnose fetal alcohol spectrum disorders with 3dMD

Date: October 10, 2013 Source: Indiana University, IT News & Events BLOOMINGTON, Ind. — Indiana University received a $125,000 grant renewal from the National Institutes of Health for ongoing research into detecting fetal alcohol spectrum disorders, a leading but preventable cause of birth defects. IU has been engaged in the Collaborative Initiative on Fetal Alcohol […]

Read More
B_ACPA2013

Automated Three Dimensional (3D) Measures of the Static Face in Normal and Dysmorphic Conditions: Novel Technology for Facial Measurement. CA Trotman, C Heaston, C Phillips, A Mercado, N Lee, T Hartman.

Date: May 2013 Source: 12th International Congress on Cleft Lip/Palate and Related Craniofacial Anomalies, Lake Buena Vista, Florida Abstract: #1772 Authors: CA Trotman, C Heaston, C Phillips, A Mercado, N Lee, T Hartman. School of Dentistry, University of North Carolina at Chapel Hill, USA.

Read More
B_BioIT World

3D Imaging and Informatics Approaches to Diagnose Genetic Conditions. C Deutsch.

Date: April 2013. Source: 2013 Bio-IT World Conference & Expo; Boston, USA. Abstract: With the support of NIH, we have developed the first quantitative normative database to diagnose craniofacial abnormalities. This new informatics resource, combined with novel methods in 3D surface imaging and 3D morphometry, provides the means of defining features of medical genetic conditions. […]

Read More
B_J of Craniofacial surgery

Soft-Tissue Volumetric Changes Following Monobloc Distraction Procedure: Analysis Using Digital Three-Dimensional Photogrammetry System (3dMD). FC Chan, HK Kawamoto, C Federico, JP Bradley.

Date: March 2013. Source: Journal of Craniofacial Surgery, Volume 24, Issue 2, pp 416-420. Abstract: We have previously reported that monobloc advancement by distraction osteogenesis resulted in decreased morbidity and greater advancement with less relapse compared with acute monobloc advancement with bone grafting. In this study, we examine the three-dimensional (3D) volumetric soft-tissue changes in […]

Read More
B_Amer_J_Physical Anthropology

Trisomy 21 and Facial Developmental Instability. JM Starbuck, TM Cole III, RH Reeves, and JT Richtsmeier.

Date: February 2013. Source: American Journal of Physical Anthropology, Volume 151, Issue 1, pp 49-57. Abstract: The most common live-born human aneuploidy is trisomy 21, which causes Down syndrome (DS). Dosage imbalance of genes on chromosome 21 (Hsa21) affects complex gene-regulatory interactions and alters development to produce a wide range of phenotypes, including characteristic facial dysmorphology. Little is known about how […]

Read More
B_Human Mutation

The facial evolution: looking backward and moving forward. G Baynam, M Walters, P Claes, S Kung, P LeSouef, H Dawkins, D Gillett, J Goldblatt.

Date: January 2013. Source: Human Mutation; 34(1): pp 14-22. Abstract: Three-dimensional (3D) facial analysis is ideal for high-resolution, nonionizing, noninvasive objective, high-throughput phenotypic, and phenomic studies. It is a natural complement to (epi)genetic technologies to facilitate advances in the understanding of rare and common diseases. The face is uniquely reflective of the primordial tissues, and […]

Read More
B_Alcoholism

Relation Over Time Between Facial Measurements and Cognitive Outcomes in Fetal Alcohol-Exposed Children. T Foroud, L Wetherill, S Vinci-Booher, ES Moore, RE Ward, HE Hoyme, LK Robinson, J Rogers, EM Meintjes, CD Molteno, JL Jacobson, SW Jacobson.

Date: September 2012. Source: Alcoholism: Clinical and Experimental Research, Volume 36, Issue 9, pages 1634–1646, September 2012. Background: The identification of individuals exposed prenatally to alcohol can be challenging, with only those having the characteristic pattern of facial features, central nervous system abnormality, and growth retardation receiving a clinical diagnosis of fetal alcohol syndrome (FAS). […]

Read More
B_bbc

BBC News: London’s Science Museum to scan visitors’ faces in 3D

Date: 17 January 2012. Source: BBC News: http://www.bbc.co.uk/news/health-16549098 Article: Visitors to London’s Science Museum are being invited to have their faces scanned in 3D. The Me in 3D stand at the museum uses a series of cameras to build a virtual image visitors can then view and manipulate. Data from participants will be used by […]

Read More