A predictive model for obstructive sleep apnea and Down syndrome. BG Skotko et al.
Date: January 2017 Source: American Journal of Medical Genetics. Abstract: Obstructive sleep apnea (OSA) occurs frequently in people with Down syndrome (DS) with reported prevalences ranging between 55% and 97%, compared to 1–4% in the neurotypical pediatric population. Sleep studies are often uncomfortable, costly, and poorly tolerated by individuals with DS. The objective of this […]Read More
A comparison of soft tissue topographical norms for the local ethnic people of Zimbabwe and African American norms based on 3dMD soft tissue photography. E Bhaskar.
Date: December 2016. Source: Master of Science Thesis, The University of Alabama at Birmingham. Introduction: The purpose of this study is to determine the soft tissue topographical norms for the local ethnic people of Zimbabwe and compare them with the African American norms based on 3dMD soft tissue photography. The rationale for the study is […]Read More
The course of positional cranial deformation from 3 to 12 months of age and associated risk factors: a follow-up with 3D imaging. H Aarnivala, V Vuollo, V Harila, T Heikkinen, P Pirttiniemi, L Holmström, AM Valkama.
Date: Source: European Journal of Pediatrics, pp 1–11. doi:10.1007/s00431-016-2773-z Abstract: Deformational plagiocephaly is reported in up to 46.6 % of healthy infants, with the highest point prevalence at around 3 months of age. Few prospective studies on the natural course of skull deformation have been conducted, and we know of no studies using 3D imaging […]Read More
Genetic and Environmental Contributions to Facial Morphological Variation: A 3D Population-Based Twin Study. J Djordjevic, AI Zhurov, S Richmond, Visigen Consortium.
Date: September 2016 Source: PLoS One. 11(9):e0162250. Introduction: Facial phenotype is influenced by genes and environment; however, little is known about their relative contributions to normal facial morphology. The aim of this study was to assess the relative genetic and environmental contributions to facial morphological variation using a three-dimensional (3D) population-based approach and the classical […]Read More
Genome-Wide Association Study Reveals Multiple Loci Influencing Normal Human Facial Morphology. JR Shaffer, E Orlova, MK Lee, EJ Leslie, ZD Raffensperger, CL Heike, more…
Date: August 2016 Source: PLOS Genetics Abstract: Numerous lines of evidence point to a genetic basis for facial morphology in humans, yet little is known about how specific genetic variants relate to the phenotypic expression of many common facial features. We conducted genome-wide association meta-analyses of 20 quantitative facial measurements derived from the 3D surface […]Read More
Heritability maps of human face morphology through large-scale automated three-dimensional phenotyping. D Tsagkrasoulis, P Hysi, T Spector, G Montana.
Date: August 2016 Source: ResearchGate Abstract: The human face is a complex trait under strong genetic control, as evidenced by the striking visual similarity between twins. Nevertheless, heritability estimates of facial traits have often been surprisingly low or difficult to replicate. Furthermore, the construction of facial phenotypes that correspond to naturally perceived facial features remains […]Read More
Multiscale Mechano-Biological Finite Element Modelling of Oncoplastic Breast Surgery—Numerical Study towards Surgical Planning and Cosmetic Outcome Prediction. Vavourakis V, Eiben B, Hipwell JH, Williams NR, Keshtgar M, Hawkes DJ.
Date: July 2016 Source: PLoS ONE 11(7): e0159766. Abstract: Surgical treatment for early-stage breast carcinoma primarily necessitates breast conserving therapy (BCT), where the tumour is removed while preserving the breast shape. To date, there have been very few attempts to develop accurate and efficient computational tools that could be used in the clinical environment for […]Read More
Hypertelorism and Orofacial Clefting Revisited: An Anthropometric Investigation. SM Weinberg, EJ Leslie, JT Hecht, GL Wehby, FWB Deleyiannis, LM Moreno, K Christensen, ML Marazita.
Date: June 2016. ONLINE AHEAD OF PRINT Source: The Cleft Palate-Craniofacial Journal. Objective: Since the 1960s, multiple studies have reported a tendency toward hypertelorism in individuals with nonsyndromic orofacial clefts (OFCs). However, the association between specific cleft types and increased interorbital distance has been inconsistent. Using three-dimensional (3D) surface imaging, we tested whether different forms […]Read More
Measuring Symmetry in Children With Unrepaired Cleft Lip: Defining a Standard for the Three-Dimensional Mid-facial Reference Plane. J Wu, C Heike, C Birgfeld, K Evans, M Maga, C Morrison, B Saltzman, L Shapiro, R Tse.
Date: March 2016 (Online ahead of print) Source: The Cleft Palate-Craniofacial Journal. Objective: Quantitative measures of facial form to evaluate treatment outcomes for cleft lip (CL) are currently limited. Computer-based analysis of three-dimensional (3D) images provides an opportunity for efficient and objective analysis. The purpose of this study was to define a computer-based standard of […]Read More
Measuring Symmetry in Children With Cleft Lip. Part 2: Quantification of Nasolabial Symmetry Before and After Cleft Lip Repair. J Wu, S Liang, L Shapiro, R Tse.
Date: December 2015. Source: The Cleft Palate-Craniofacial Journal. Objective: The first part of this study validated an automated computer-based method of identifying the three-dimensional midfacial plane in children with unrepaired cleft lip. The purpose of this second part is to develop computer-based methods to quantify symmetry and to determine the correlation of these measures to […]Read More
The 3D Facial Norms Database: Part 1. A Web-Based Craniofacial Anthropometric and Image Repository for the Clinical and Research Community.
Date: October 2015 [Epub ahead of print]. Source: Cleft Palate Craniofacial Journal. Background: Although craniofacial sex differences have been extensively studied in humans, relatively little is known about when various dimorphic features manifest during postnatal life. Using cross-sectional data derived from the 3D Facial Norms data repository, we tested for sexual dimorphism of craniofacial soft-tissue […]Read More
Evaluating 3-Dimensional Soft Tissue Changes in Class III Chinese Patients after Orthognathic Surgery. JX Su, M Yow, MT Chew, HC Wong.
Date: September 2015. Source: 8th International Orthodontic Congress 2015, London. Aim: To evaluate facial soft tissue changes in Class III skeletal Chinese patients who have undergone orthognathic surgery. Objective. To determine if there is a correlation between hard and soft tissue movement after orthognathic surgery. Study Design: This is a retrospective study involving 15 Chinese […]Read More
A Morphable Profile Model of the Human Head as an Outcome Tool for Craniosynostosis Surgery, C Duncan, R Armstrong, NE Pears.
Date: September 15, 2015. Source: 16th Congress of International Society of Craniofacial Surgery (ISCFS) 2015. Presenter: C Duncan. Introduction: Outcome analysis in craniosynostosis surgery is difficult and often relies on limited anthropometric measurement, qualitative analysis of photography or patient reported outcome. Quantifiable morphable models of the human face have been described but, to date, a […]Read More
This 4D scanner captures your unique bodily ‘jiggle,’ by Liat Clark.
Date: 11 August 15 Headline: This 4D scanner captures your unique bodily ‘jiggle’ by Liat Clark Source: http://www.wired.co.uk/news/archive/2015-08/11/modelling-body-fat-jiggle-in-4d The future avatars we embody will show every lump, bump and jiggle of our soft human flesh – and you have tech to thank. A team at the Max Planck Institute for Intelligent Systems (MPI-IS) has developed […]Read More
Craniofacial Image Analysis. E Mercan, I Atmosukarto, J Wu, S Liang, LG Shapiro.
Date: July 2015. Source: Health Monitoring and Personalized Feedback using Multimedia Data. Springer. Abstract: Craniofacial researchers have used anthropometric measurements taken directly on the human face for research and medical practice for decades. With the advancements in 3D imaging technologies, computational methods have been developed for the diagnoses of craniofacial syndromes and the analysis of […]Read More
Comparison of the Facial Morphologies of Identical Twins Using Three-Dimensional Photography: A Case Report. Sedat Altindis, Erdem Hatunoglu, Emine Toptan.
Date: July 2015 Source: Medicine Science | International Medical Journal. Abstract: The facial morphologies of identical twins were compared using the 3dMD three-dimensional (3D) photogrammetry system. 3D images of the faces of 27-year-old identical twins were acquired and then superimposed. The differences were shown in a color histogram generated using 3dMD Vultus software. The faces […]Read More
Thesis: Three-dimensional age-related changes of the adult face: African American female population. TC Sutherland.
Date: June 2015 Source: Theses. ProQuest, Publication No. 1587083. University of Alabama at Birmingham. Adviser: Chung H. Kau Abstract: Treatment of older adults is one of the fastest growing areas in orthodontic practice. The objectives of this study are to: 1. Investigate the aging of the female African American face using three-dimensional surface imaging to […]Read More
Thesis: Investigating the Accuracy and Reproducibility of 3dMDface System for Soft Tissue Analysis. YM Kachroo.
Date: June 2015. Source: Theses. ProQuest, Publication No. 1590412. University of California, Los Angeles. Advisers: Yeumin Hong; Won Moon. Objective: Three-dimensional (3D) soft tissue (ST) changes from orthodontic treatment can now be evaluated with the development of 3D photography. However, the accuracy and reliability of this method is still in question. This study aims to […]Read More
Three-dimensional human facial morphologies as robust aging markers. W Chen, W Qian, G Wu, W Chen, B Xian, X Chen, Y Cao, CD Green, F Zhao, K Tang, JD Han.
Date: May 2015. Source: Journal of Cell Research, 25, 574-587. Abstract: Aging is associated with many complex diseases. Reliable prediction of the aging process is important for assessing the risks of aging-associated diseases. However, despite intense research, so far there is no reliable aging marker. Here we addressed this problem by examining whether human 3D […]Read More
Comparing Facial 3D Analysis With DNA Testing to Determine Zygosities of Twins. V Vuollo, M Sidlauskas, A Sidlauskas, V Harila, L Salomskiene, A Zhurov, L Holmström, P Pirttiniemi, T Heikkinen.
Date: June 2015. Source: Twin Research and Human Genetics, Volume 18, Issue 03, pp 306-313. Abstract: The aim of this study was to compare facial 3D analysis to DNA testing in twin zygosity determinations. Facial 3D images of 106 pairs of young adult Lithuanian twins were taken with a stereophotogrammetric device (3dMD, Atlanta, Georgia) and […]Read More
Validation of a new method to measure facial soft tissue movements. CA Trotman, T Lu, V Sirianna.
Date: May 2015. Source: International Association for Dental Research, Boston, USA. Poster: #4342. Authors: CA Trotman, T Lu, V Sirianna. School of Dentistry, University of North Carolina at Chapel Hill, USA.Read More
Posterior cranial vault distraction in the management of syndromic multi-suture craniosynostosis: Outcomes and 3D photographic/CT-based morphometric analysis. CR Forrest, BM French, A Clausen.
Date: April 11-14, 2015. Source: AAPS 94th Annual Meeting, Scottsdale, AZ, USA. PURPOSE: Posterior cranial vault distraction has recently been popularized as a first intervention technique in the management of syndromic and multi-suture craniosynostosis. The purpose of this study was to present our experience with posterior cranial vault distraction in the management of these complex […]Read More
Monitoring of Therapy for Mucopolysaccharidosis Type I Using Dysmorphometric Facial Phenotypic Signatures. Stefanie Kung, M Walters, P Claes, P LeSouef, J Goldblatt, A Martin, S Balasubramaniam, G Baynam.
Date: March 2015. Source: JIMD Reports 2015, Springer. Abstract: There is a pattern of progressive facial dysmorphology in mucopolysaccharidosis type I (MPS I). Advances in 3D facial imaging have facilitated the development of tools, including dysmorphometrics, to objectively and precisely detect these facial phenotypes. Therefore, we investigated the application of dysmorphometrics as a noninvasive therapy-monitoring […]Read More
Prenatal sex hormones, digit ratio, and face shape in adult males. SM Weinberg, TE Parsons, ZD Raffensperger.
Date: February 2015. Source: Orthodontics & Craniofacial Research, 18(1):21-6. Objectives: Several reports have demonstrated a relationship between second to fourth digit ratio (2D:4D) and facial shape, suggesting that prenatal sex hormones play a role in the development of the craniofacial complex. Using 3D surface imaging and geometric morphometrics, we test the hypothesis that decreased digit […]Read More
Variation and signatures of selection on the human face. J Guo, J Tan, Y Yang, H Zhou, S Hu, A Hashan, N Bahaxar, S Xu, TD Weaver, L Jin, M Stoneking, K Tang.
Date: October 2014 Source: Journal of Human Evolution. Volume 75, pp 143–152. Abstract: There has been much debate about why humans throughout the world differ in facial form. Previous studies of human skull morphology found levels of among-population differentiation that were comparable to those of neutral genetic markers, suggesting that genetic drift (neutral processes) played […]Read More
Biomedical visual data analysis to build an intelligent diagnostic decision support system in medical genetics. K Kuru, M Niranjan, Y Tunca, E Osvank, T Azim.
Date: October 2014. Source: Artificial Intelligence in Medicine, 62(2):105-18. Background: In general, medical geneticists aim to pre-diagnose underlying syndromes based on facial features before performing cytological or molecular analyses where a genotype–phenotype interrelation is possible. However, determining correct genotype–phenotype interrelationships among many syndromes is tedious and labor-intensive, especially for extremely rare syndromes. Thus, a computer-aided […]Read More
Perceptual differences between men and women: A 3D facial morphometric perspective. S Gilani, A Mian.
Date: August 2014 Source: Int. Conference on Pattern Recognition (ICPR) 2014, Stockholm, Sweden. © IEEE. pp 2413 – 2418. Abstract: Understanding the features employed by the human visual system in gender classification is considered a critical step towards improving machine based gender classification systems. We propose the use of 3D Euclidean and geodesic distances between […]Read More
Exploratory genotype–phenotype correlations of facial form and asymmetry in unaffected relatives of children with non-syndromic cleft lip and/or palate. SF Miller, SM Weinberg, NL Nidey, DK Defay, ML Marazita, GL Wehby, LM Moreno Uribe.
Date: June 2014 Source: Journal of Anatomy, Volume 224, Issue 6, pp 688-709. Abstract: Family relatives of children with nonsyndromic cleft lip with or without cleft palate (NSCL/P) who presumably carry a genetic risk yet do not manifest overt oral clefts, often present with distinct facial morphology of unknown genetic etiology. This study investigates distinct […]Read More
Modeling 3D Facial Shape from DNA. P Claes, DK Liberton, K Daniels, KM Rosana, EE Quillen, LN Pearson, B McEvoy, M Bauchet, AA Zaidi, W Yao, H Tang, GS Barsh, DM Absher, MD Shriver.
Date: March 2014 Source: PLOS Genetics. Abstract: Human facial diversity is substantial, complex, and largely scientifically unexplained. We used spatially dense quasi-landmarks to measure face shape in population samples with mixed West African and European ancestry from three locations (United States, Brazil, and Cape Verde). Using bootstrapped response-based imputation modeling (BRIM), we uncover the relationships […]Read More
Digital imaging analysis to assess scar phenotype. BJ Smith, N Nidey, SF Miller, LMM Uribe, CL Baum, GS Hamilton, GL Wehby, M Dunnwald.
Date: March-April 2014. Source: Wound Repair and Regeneration, Volume 22, Issue 2, pages 228–238. Abstract: In order to understand the link between the genetic background of patients and wound clinical outcomes, it is critical to have a reliable method to assess the phenotypic characteristics of healed wounds. In this study, we present a novel imaging […]Read More
The cluster assessment of facial attractiveness using fuzzy neural network classifier based on 3D Moiré features. WC Chiang, HH Lin, CS Huang, LJ Lo, SY Wan.
Date: March 2014. Source: Pattern Recognition. Volume 47, Issue 3, pp 1249–1260. Abstract: Facial attractiveness has long been argued upon varied emphases by philosophers, artists, psychologists and biologists. A number of studies empirically investigated how facial attractiveness was influenced by 2D facial characteristics, such as symmetry, averageness and golden ratio. However, few implementations of facial […]Read More
Detecting Genetic Association of Common Human Facial Morphological Variation Using High Density 3D Image Registration. S Peng, J Tan, S Hu, H Zhou, J Guo, L Jin, K Tang.
Date: December 2013. Source: PLoS Computational Biology, Public Library of Science. Abstract: Human facial morphology is a combination of many complex traits. Little is known about the genetic basis of common facial morphological variation. Existing association studies have largely used simple landmark-distances as surrogates for the complex morphological phenotypes of the face. However, this can […]Read More
BBC: Defining the most ‘normal’ shape of a human skull.
Date: 22 November 2013 Source: BBC News Article: Defining the most ‘normal’ shape of a human skull Reconstructive surgery for people born with a misshapen skull is one of medicine’s most complicated challenges. Part of the problem for surgeons is defining what a normal head actually looks like. A team of Liverpool-based surgeons, and artists, […]Read More
Indiana University visualization experts help doctors diagnose fetal alcohol spectrum disorders with 3dMD
Date: October 10, 2013 Source: Indiana University, IT News & Events BLOOMINGTON, Ind. — Indiana University received a $125,000 grant renewal from the National Institutes of Health for ongoing research into detecting fetal alcohol spectrum disorders, a leading but preventable cause of birth defects. IU has been engaged in the Collaborative Initiative on Fetal Alcohol […]Read More
Be Part of the Alder Hey Children’s Hospital Headspace Project and Change Lives!
Liverpool, United Kingdom (24-September-13): Alder Hey Children’s Hospital and FACT are looking for volunteers to take part in a groundbreaking project which will impact on the future development of craniofacial surgery. The Headspace project, created by Alder Hey in conjunction with FACT and associated artists will develop a comprehensive database of human head shapes using […]Read More
BBC News: Cardiff University uses 3D scans to help facial surgery.
Date: 2 August 2013 Source: BBC News News: Cardiff University uses 3D scans to help facial surgery. Patients who need facial surgery and those recovering from strokes could benefit from world-leading research of analysing facial movements in 3D. Scientists at Cardiff University are using cutting-edge face scanners developed by American firm 3dMD. The technology can […]Read More
Cardiff Scientists and 3dMD Enter a New Dimension in 3D/4D Facial Imaging.
Anaheim, California (23-July-13): A team of Cardiff University clinicians and computer scientists can, for the first time, carry out facial movement research and transform the way patients needing facial surgery are assessed and monitored thanks to a new state-of-the-art 3D surface motion imaging system from 3dMD (3dMD exhibiting at #SIGGRAPH2013 Booth 226). Working alongside the […]Read More
Improved Detection of Landmarks on 3D Human Face Data. S Liang; S Weinberg; L Shapiro.
Date: July 2013. Source: IEEE Engineering in Medicine and Biology Society Annual Conference. Abstract: Craniofacial researchers make heavy use of established facial landmarks in their morphometric analyses. For studies on very large facial image datasets, the standard approach of manual landmarking is very labor intensive. With the goal of producing 20 established landmarks, we have […]Read More
The Use of Pseudo-landmarks for Craniofacial Analysis: A Comparative Study with L1 Regularized Logistic Regression. E Mercan; L Shapiro; S Weinberg; SI Lee.
Date: July 2013. Source: IEEE Engineering in Medicine and Biology Society Annual Conference. Abstract: Morphometrics, the quantitative analysis of shape, is used by craniofacial researchers to study abnormalities in human face shapes. Most of the work in craniofacial morphometrics uses landmark points that are manually marked on 3D face data and processed via a generalized […]Read More
Automated Three Dimensional (3D) Measures of the Static Face in Normal and Dysmorphic Conditions: Novel Technology for Facial Measurement. CA Trotman, C Heaston, C Phillips, A Mercado, N Lee, T Hartman.
Date: May 2013 Source: 12th International Congress on Cleft Lip/Palate and Related Craniofacial Anomalies, Lake Buena Vista, Florida Abstract: #1772 Authors: CA Trotman, C Heaston, C Phillips, A Mercado, N Lee, T Hartman. School of Dentistry, University of North Carolina at Chapel Hill, USA.Read More
The facial evolution: looking backward and moving forward. G Baynam, M Walters, P Claes, S Kung, P LeSouef, H Dawkins, D Gillett, J Goldblatt.
Date: January 2013. Source: Human Mutation; 34(1): pp 14-22. Abstract: Three-dimensional (3D) facial analysis is ideal for high-resolution, nonionizing, noninvasive objective, high-throughput phenotypic, and phenomic studies. It is a natural complement to (epi)genetic technologies to facilitate advances in the understanding of rare and common diseases. The face is uniquely reflective of the primordial tissues, and […]Read More
3D comparison of average faces in subjects with oral clefts. I Bugaighis, B Tiddeman, CR Mattick and R Hobson
Date: November 2012 Source: European Journal of Orthodontics Abstract: This prospective cross-sectional, case-controlled morphometric study assessed three dimensional (3D) facial morphological differences between average faces of 103 children aged 8-12 years; 40 with unilateral cleft lip and palate (UCLP), 23 with unilateral cleft lip and alveolus (UCLA), 19 with bilateral cleft lip and palate (BCLP), […]Read More
Relation Over Time Between Facial Measurements and Cognitive Outcomes in Fetal Alcohol-Exposed Children. T Foroud, L Wetherill, S Vinci-Booher, ES Moore, RE Ward, HE Hoyme, LK Robinson, J Rogers, EM Meintjes, CD Molteno, JL Jacobson, SW Jacobson.
Date: September 2012. Source: Alcoholism: Clinical and Experimental Research, Volume 36, Issue 9, pages 1634–1646, September 2012. Background: The identification of individuals exposed prenatally to alcohol can be challenging, with only those having the characteristic pattern of facial features, central nervous system abnormality, and growth retardation receiving a clinical diagnosis of fetal alcohol syndrome (FAS). […]Read More
No evidence for sexual dimorphism of facial width-to-height ratio in four large adult samples. CE Lefevrea, GJ Lewisb, TC Batesc, M Dzhelyovaa, V Coetzeed, IJ Dearyc, DI Perretta.
Date: June 2012. Source: Evolution & Human Behavior. Volume 33, Issue 6 , Pages 623-627. Abstract: Sexual dimorphism in physical appearance may be an important cue in both intra- and intersex competition. Recently, the facial width-to-height ratio (fWHR) has been proposed as a novel sexually dimorphic morphologic measure, with men suggested to have a higher […]Read More
Dysmorphometrics: the Modelling of Morphological Abnormalities. P Claes, K Daniels, M Walters, J Clement, D Vandermeulen and P Suetens.
Date: February 2012. Source: Theoretical Biology and Medical Modelling, Volume 9:5, Feb 2012. Background: The study of typical morphological variations using quantitative, morphometric descriptors has always interested biologists in general. However, unusual examples of form, such as abnormalities are often encountered in biomedical sciences. Despite the long history of morphometrics, the means to identify and […]Read More
BBC News: London’s Science Museum to scan visitors’ faces in 3D
Date: 17 January 2012. Source: BBC News: http://www.bbc.co.uk/news/health-16549098 Article: Visitors to London’s Science Museum are being invited to have their faces scanned in 3D. The Me in 3D stand at the museum uses a series of cameras to build a virtual image visitors can then view and manipulate. Data from participants will be used by […]Read More
BBC News: 3D face scan to help future surgery.
Date: 17 January 2012. Source: BBC News: http://www.bbc.co.uk/news/science-environment-16588956 Article: 3D face scan to help future surgery. Visitors to London’s Science Museum are being invited to have their faces scanned in 3D. The ‘Me in 3D’ exhibit uses an array of cameras to build a virtual image visitors can then view and manipulate. Data from the […]Read More
See yourself in 3D at the London Science Museum
LONDON (3 January 2012) – How are our faces constructed? How does your face differ from other faces? What do you look like in another dimension? These questions will be explored in Me in 3D – a new event running from 11 January until 10 April, where visitors can volunteer to have their photograph taken […]Read More
Three-dimensional gender differences in facial form of children in the North East of England. I Bugaighis, C Mattick, B Tiddeman, and R Hobson
Date: April 2011 (Epub) Source: European Journal of Orthodontics Abstract: The aim of the prospective cross-sectional morphometric study was to explore three dimensional (3D) facial shape and form (shape plus size) variation within and between 8- and 12-year-old Caucasian children; 39 males age-matched with 41 females. Article: Three-dimensional gender differences in facial form of children […]Read More